Scientific Literature Lyme Disease

  1. Schriefer ME. Lyme Disease Diagnosis: Serology. Clin Lab Med. 2015;35(4):797-814. doi: 10.1016/j.cll.2015.08.001. PubMed PMID: 26593258.
  2. Borchers AT, Keen CL, Huntley AC, Gershwin ME. Lyme disease: a rigorous review of diagnostic criteria and treatment. Journal of autoimmunity. 2015;57:82-115. doi: 10.1016/j.jaut.2014.09.004. PubMed PMID: 25451629.
  3. Kuehn BM. CDC estimates 300,000 US cases of Lyme disease annually. JAMA. 2013;310(11):1110. doi: 10.1001/jama.2013.278331. PubMed PMID: 24045727.
  4. Aguero-Rosenfeld ME, Wormser GP. Lyme disease: diagnostic issues and controversies. Expert Rev Mol Diagn. 2015;15(1):1-4. doi: 10.1586/14737159.2015.989837. PubMed PMID: 25482091.
  5. Naleway AL, Belongia EA, Kazmierczak JJ, Greenlee RT, Davis JP. Lyme disease incidence in Wisconsin: a comparison of state-reported rates and rates from a population-based cohort. Am J Epidemiol. 2002;155(12):1120-7. PubMed PMID: 12048226.
  6. Smith RP, Schoen RT, Rahn DW, Sikand VK, Nowakowski J, Parenti DL, Holman MS, Persing DH, Steere AC. Clinical characteristics and treatment outcome of early Lyme disease in patients with microbiologically confirmed erythema migrans. Ann Intern Med. 2002;136(6):421-8. PubMed PMID: 11900494.
  7. Wormser GP, McKenna D, Carlin J, Nadelman RB, Cavaliere LF, Holmgren D, Byrne DW, Nowakowski J. Brief communication: hematogenous dissemination in early Lyme disease. Ann Intern Med. 2005;142(9):751-5. PubMed PMID: 15867407.
  8. Centers for Disease C, Prevention. Recommendations for test performance and interpretation from the Second National Conference on Serologic Diagnosis of Lyme Disease. MMWR Morb Mortal Wkly Rep. 1995;44(31):590-1. PubMed PMID: 7623762.
  9. Branda JA, Aguero-Rosenfeld ME, Ferraro MJ, Johnson BJ, Wormser GP, Steere AC. 2-tiered antibody testing for early and late Lyme disease using only an immunoglobulin G blot with the addition of a VlsE band as the second-tier test. Clin Infect Dis. 2010;50(1):20-6. doi: 10.1086/648674. PubMed PMID: 19947857.
  10. Branda JA, Linskey K, Kim YA, Steere AC, Ferraro MJ. Two-tiered antibody testing for Lyme disease with use of 2 enzyme immunoassays, a whole-cell sonicate enzyme immunoassay followed by a VlsE C6 peptide enzyme immunoassay. Clin Infect Dis. 2011;53(6):541-7. doi: 10.1093/cid/cir464. PubMed PMID: 21865190.
  11. Branda JA, Strle F, Strle K, Sikand N, Ferraro MJ, Steere AC. Performance of United States serologic assays in the diagnosis of Lyme borreliosis acquired in Europe. Clin Infect Dis. 2013;57(3):333-40. doi: 10.1093/cid/cit235. PubMed PMID: 23592827.
  12. Steere AC, McHugh G, Damle N, Sikand VK. Prospective study of serologic tests for lyme disease. Clin Infect Dis. 2008;47(2):188-95. doi: 10.1086/589242. PubMed PMID: 18532885.
  13. Wormser GP, Liveris D, Hanincova K, Brisson D, Ludin S, Stracuzzi VJ, Embers ME, Philipp MT, Levin A, Aguero-Rosenfeld M, Schwartz I. Effect of Borrelia burgdorferi genotype on the sensitivity of C6 and 2-tier testing in North American patients with culture-confirmed Lyme disease. Clin Infect Dis. 2008;47(7):910-4. doi: 10.1086/591529. PubMed PMID: 18724824; PMCID: PMC2773679.
  14. Wormser GP, Nowakowski J, Nadelman RB, Visintainer P, Levin A, Aguero-Rosenfeld ME. Impact of clinical variables on Borrelia burgdorferi-specific antibody seropositivity in acute-phase sera from patients in North America with culture-confirmed early Lyme disease. Clin Vaccine Immunol. 2008;15(10):1519-22. doi: 10.1128/CVI.00109-08. PubMed PMID: 18716009; PMCID: PMC2565926.
  15. Feder HM, Jr., Hoss DM, Zemel L, Telford SR, 3rd, Dias F, Wormser GP. Southern Tick-Associated Rash Illness (STARI) in the North: STARI following a tick bite in Long Island, New York. Clin Infect Dis. 2011;53(10):e142-6. doi: 10.1093/cid/cir553. PubMed PMID: 21940418.
  16. Kalish RA, McHugh G, Granquist J, Shea B, Ruthazer R, Steere AC. Persistence of immunoglobulin M or immunoglobulin G antibody responses to Borrelia burgdorferi 10-20 years after active Lyme disease. Clin Infect Dis. 2001;33(6):780-5. doi: 10.1086/322669. PubMed PMID: 11512082.
  17. Kowalski TJ, Tata S, Berth W, Mathiason MA, Agger WA. Antibiotic treatment duration and long-term outcomes of patients with early lyme disease from a lyme disease-hyperendemic area. Clin Infect Dis. 2010;50(4):512-20. doi: 10.1086/649920. PubMed PMID: 20070237.
  18. Peltomaa M, McHugh G, Steere AC. Persistence of the antibody response to the VlsE sixth invariant region (IR6) peptide of Borrelia burgdorferi after successful antibiotic treatment of Lyme disease. J Infect Dis. 2003;187(8):1178-86. doi: 10.1086/374376. PubMed PMID: 12695996.

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